The Met Office warning says: "Possibility of heavy snow over parts of England, Wales and southern Scotland".
However heavy rain and even possible hill snow is likely later on Easter Sunday and into Monday.
"Where there are impacts from this they could be significant and we could see snow to low levels for a time".
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However, the warning adds that "it is quite possible that snow might not be too disruptive".
Prolonged periods of rain and snow are forecast to lash Britain in the coming days as the weather turns "generally unsettled and cold" during Easter.
After a chilly, dry and bright start on Friday, outbreaks of rain will edge north through the day. Expect mostly rain south and mostly snow north along the ND border. "Most likely to rain down towards the south".
Monday night, there will be a 30 percent chance of showers, with a low of 41, according to the weather service.
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Saturday will turn drier, brighter and colder with a brisk north easterly wind, paving the way for a "widespread frost" on Easter Sunday for much of the country and the potential of lows of -5 in parts of Scotland.
Sunday is forecast to be a much calmer day, with more settled conditions and spells of sunshine, despite some rain in northern England.
The mean temperature was 2.2°C (36°F) - more than 3°C colder than the long-term monthly average.
Saturday, the high will be near 57 with partly sunny skies and a southwest wind of 11 to 15 miles per hour, becoming north in the afternoon, according to the weather service. But driving could be tricky with blowing snow in the air. The snow remained on the ground until early April.
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