And Kane was furious that his side were denied a point against Luis Enrique's side.
"In those big environments you need the ref to stay strong and unfortunately he's bottled it".
"They passed it around very well in the first half, we talked about that coming out into the second".
"Danny's just stood there, and De Gea's gone up and he's caught the ball but as he's come down he's fallen on top of Danny".
England's defeat was their first in 25 competitive fixtures at Wembley.
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Southgate said: "Harry will not play. I said right across the summer, we're under no illusions about that, but also we are prepared for that challenge".
Gareth Southgate has had "initial discussions" over extending his England manager contract but for now is only "focusing on the job in hand".
Rashford would have had a second ten minutes before the break but for a stunning reaction save from his Manchester United team-mate De Gea.
"I think at the moment we have to stick with the plan, stick with what we're doing and just get better at doing it".
'We want to test ourselves against the best and we put up a fight. We represent England and it's great to play around the country.
"Their retention of the ball was top class".
"Yeah, a little bit", said Liverpool captain Henderson.
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"We aren't able to do that when teams press high against us yet".
I believe I've been through an experience that is as pressured as you're ever going to face at any club or worldwide team in getting through a World Cup, so I'm totally comfortable with that, and what's beyond that is to be decided.
Trippier added: 'From my angle I had a very good view of it.
"So, given where we're at and we need those experiences to improve and I couldn't ask any more of the players".
Spain returned to winning ways with their 2-1 victory over England on Saturday after their disastrous time at the World Cup but the most striking element of their performance at Wembley was the new identity they are forming under coach Luis Enrique.
Southgate could conceivably have picked a far stronger side and his decision to experiment this way is a bold one when, despite everything England achieved at the World Cup, the paradox is that his win percentage, 50%, is now no better than Steve McClaren's time in charge.
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